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Cancer Therapy

Tailor-made cancer drugs: Wave of the future?

Published in Cancer Weekly, November 26th, 2002

Today, even the best cancer treatments kill about as many healthy cells as they do cancer cells, but John-Stephen A. Taylor, PhD, professor of chemistry at Washington University in St. Louis, has a plan to improve that ratio.

Over the last several years, Taylor has begun to lay the conceptual and experimental groundwork for a radical new strategy for chemotherapy - one that turns existing drugs into medicinal "smart bombs," if you will.

All DNA is formed of three basic components: a phosphate and a sugar, which combine to form the sides of the double helix "ladder," and a base that forms the ladder's "rungs." All variances in DNA, including...

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