Published in Cancer Weekly, December 3rd, 2002
"Sensory neuropathies are a frequent and dose-limiting complication resulting from treatment with cisplatin," stated P.F. Pradat and colleagues, Hopital La Pitie Salpetriere, Paris, France.
"Neurotrophin-3 (NT-3) promotes the survival of the large fiber sensory neurones that are impaired in cisplatin-induced neuropathy, and may therefore serve as a preventive agent. However, the short half-life of recombinant NT-3 after systemic...
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