Pancreatic Cancer Therapy
Gene transfer shuts down pancreatic tumors in cancer models
Published in Cancer Weekly, December 17th, 2002
Researchers who work for INSERM in Toulouse, France, used somatostatin receptor subtype 2 (sst2) gene therapy to subdue both primary and metastatic human pancreatic cancer lesions growing in immunocompromised mice. Sst2 has antioncogenic properties with a reach that extends beyond tumors treated locally, according to a new report.
Fabienne Vernejoul and colleagues said the sst2 genes, when delivered to cancer cells via adenovirus or a synthetic polycationic carrier (PEI), generated transgene expression at...
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Source: Cancer Weekly (2002-12-17)
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