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Pancreatic Cancer

T-cell targeting immunotherapy "still a hypothesis"

Published in Cancer Weekly, December 31st, 2002

Internists at Haukeland University Hospital in Norway recently commented on T-cell targeting immunotherapy for pancreatic cancer.

"Until recently," they said, "this therapeutic strategy has been used as a single specific treatment and clinical studies have demonstrated that tumor-specific T-cell responses can be induced in a subset of patients and even in patients with advanced disease. However, it remains to be demonstrated whether these T-cell responses can mediate clinically relevant antitumor reactivity."

"Furthermore, in vitro studies of cancer cell susceptibility to antitumor T-cell reactivity are often limited to cancer cell lines because...

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