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Cancer Weekly

Susan Hasty, Publisher

Table of Contents . . . January 21st, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Weekly | Other Publications

Melanoma - Soluble form of vitamin E arrests cancer cell growth

Multiple Myeloma - Oral drug combination proven as effective as standard chemotherapy

Breast Cancer - Regular mammography screening identifies breast cancer at an earlier stage

Hepatocellular Carcinoma - Synergism of alcohol with viral hepatitis and diabetes mellitus pose HCC risk

Prostate Cancer - Report shows benefits of combining vitamin D with Taxotere

Prostate Cancer - Soy product genistein quells cancer growth mechanisms at genetic level

Squamous Cell Carcinoma - Combined endostatin and EGF receptor-antisense therapy may hold promise

Thyroid Cancer - Rodent gene better than human ones for concentrating radioisotope

Antiangiogenesis - Study finds thalidomide analogues significantly more potent

Awards - U-M bone marrow transplant expert receives Doris Duke Charitable Foundation award

Brain Cancer - Antibody shows promise in Drexel trial

Brain Tumors - Study finds interleukin-2 induced antitumor activity superior to IL-12

Breast Cancer - Correlation shown between Biofield Diagnostic System, Ki-67 Antigen Expression Test

Breast Cancer - Cyr61 promotes breast tumorigenesis and cancer progression

Breast Cancer - M-CSF, IL-2 coexpression can augment the effect of HSVtk suicide gene therapy

Breast Cancer - National Cancer Institute selects breast therapeutic for further development

Breast Cancer - New role for tamoxifen as fertility drug for patients?

Breast Cancer - Promoter hypermethylation of DAP kinase gene linked to invasive lobular subtype

Breast Cancer - Tamoxifen-resistant tumors alter their traits, become receptive to new therapies

Breast Cancer - Vascularity could be warning sign for invasion in ductal carcinomas

Cancer Gene Therapy - Data reported from phase I trial of ISIS 104838

Cancer Gene Therapy - Id2 gene is novel target of EWS-ETS fusion proteins

Cancer Mortality - Britain rivals the U.S. in childhood cancer survival

Cancer Therapy - Company announces initial clinical data on oral formulation of Triapine

Cancer Therapy - INGN 241 shows antitumor activity

Cancer Vaccines - DC and CpG ODN immunotherapy cures large murine tumors that resist chemotherapy

Cancer Vaccines - HER-2-derived recombinant antigens engineered for antitumor immunotherapy

Cancer Vaccines - T-cell help required for memory cytotoxic T-cell antitumor activity

Carcinogens - Nicotine may help other cigarette chemicals to 'do their dirty work'

Cell Biology - c-Myc exerts protects against cellular insults via ornithine decarboxylase

Cervical Cancer - Risk doubles with longer screening intervals

Cervical Cancer - Vaccine causes HPV-associated tumor growth to regress in mice

Collaborations - Anticancer drug candidates to be jointly developed, marketed

Colon Cancer - Cell growth suppressed in nude mice by targeting beta-catenin/TCF pathway

Colorectal Cancer - Drug that cuts off a tumor's blood supply shows promise

Epidemiology - U.K. cancer cases on the rise - but deaths are down

Glioblastoma Multiforme - Company provides update on IL13-PE38 development program

Glioblastoma Multiforme - IL-4 Fusion Toxin (NBI-3001) results reported

Hepatitis B Genetics - Mutations differentiate chronic infection and liver cancer in children

Hepatocellular Carcinoma - Serum endostatin predicts tumor vascularity

Leukemia - ANDA approvals in 2002 will lead to four launches in 2003

Leukemia - G-CSF-primed haploidentical marrow grafts feasible, effective for high-risk patients

Liver Cancer Therapy - New imaging technique improves guidance in percutaneous ablation therapy

Lung Cancer - INDA submitted for Tc-99m Hynic-Annexin V

Lung Cancer - Mount Sinai Comprehensive Cancer Center studies drug regimens

Malignant Glioma - Positive interim safety results reported from Reolysin phase I study

Melanoma - FcgammaR-positive tumors may respond to antibody-mediated therapies

Menopause - Combination hormone therapy associated with increase in breast density

Menopause - SERMs offer safer alternative than HRT

Mesothelioma - Asbestos-cancer treatments expected to improve

Monoclonal Antibodies - IND filed for therapeutic antibody

Multiple Myeloma - Degree of bone marrow angiogenesis is a prognostic marker

Non-Hodgkin lymphoma - FDA panel supports efficacy of Bexxar in rituximab-refractory patients

Non-Small Cell Lung Cancer - Phase III SMART trial of Xcytrin begins

Nutrition - Vitamin E, other nutrients may be tailored in future to target results

Ovarian Cancer - Yale clinical trial tests new treatment approach

Pain Medicine - Substantial improvements in cancer trials not likely caused by placebo effects

Pancreatic Cancer - New data reported from phase II trial of ISIS 2503 plus chemotherapy

Pleural Mesothelioma - Exposure to contaminated poliovirus vaccine not likely linked to rare cancer

Prostate Cancer - Estimating number of radiotherapy patients can prevent staffing shortages

Prostate Cancer - FDA panel requests more data on Casodex

Prostate Cancer - Novel approach shows promise for a blood test

Prostate Cancer - Rights regained to ex vivo prostate cancer immunotherapy

Prostate Cancer - Update provided on KRX-123

Renal Cell Carcinoma - Autologous monocyte-derived dendritic cell-based immunotherapy well tolerated

Skin Cancer - Broad-spectrum ultraviolet radiation added to list of known carcinogens

Transplant Medicine - Organ retention issue deals blow to children's cancer research

Tumors - MDA-7 activates immune system, has antiangiogenic properties

Tumors - Studies show that INGN 241 activates immune system

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