Squamous Cell Carcinoma
Combined endostatin and EGF receptor-antisense therapy may hold promise
Published in Cancer Weekly, January 21st, 2003
M.F. Li and colleagues used "the 1483 cell line of human head and neck SCC (HNSCC) and SCC-VII/SF murine SCC cells ... to establish tumors in nude mice and immunocompetent C3H mice, respectively. Tumor-bearing mice were treated with endostatin (20 mg/kg/day, s.c.), liposomal EGFR-antisense expression plasmid (25 microg/mouse, three times/week, intratumoral), a combination of both agents, or liposomal EGFR-sense plasmid as a control."
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Source: Cancer Weekly (2003-01-21)
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