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Cancer Weekly

Susan Hasty, Publisher

Table of Contents . . . January 28th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Weekly | Other Publications

Cell Biology - Blocking one protein helps cancer cells die of natural causes

Prostate Cancer - Researchers zero in on cancer markers

Cancer Therapy - Trial to test new drug to boost immune system after chemotherapy

Dyskeratosis Congenita - Mutation in DKC1 gene can cause rare aging disease and cancer

Liver Cancer - Folate/methyl deficiency causes gene methylation in rat livers

Non-Small Cell Lung Cancer - Variants of growth factor linked to prognosis of lung cancer

Angiogenesis - IND filed for therapeutic with antiangiogenenic properties

Blood Testing - Clinical significance of phenotypic features of blasts in patients with myelodysplastic syndrome

Breast Cancer - Review outlines preclinical applications of transgenic mouse breast cancer models

Breast Cancer - Writing exercises may help patients

Breast Cancer Diagnosis - Contrast detail on digital mammography outpaces that of screen-film

Breast Cancer Risk Factor - Abnormal glucose metabolism linked to breast cancer

Cancer Metastasis - Glioma and melanoma tropism a hallmark for extravascular migration

Cancer Therapy - Recombinant therapy could sensitize cancer cells to retinoic acid

Cancer Vaccine - Dendritic cells generated by Flt3L or GM-CSF/IL-4 generate antileukemia response

Chronic Myeloid Leukemia - Oncogenic interaction between BCR-ABL, NUP98-HOXA9 shown by in vitro purging culture system

Collaborations - Long-term manufacturing, supply agreement signed

Colon Cancer - Sp1 transcription factor regulates thymidine phosphorylase in human carcinoma

Colorectal Cancer - Bevacizumab enhances chemotherapy in phase II trial

Dermatology - Biological response to UV-B radiation modified with DNA repair enzyme

Drug Safety - AstraZeneca to review distribution of anticancer drug in Japan

Gene Targeting - Vascular-targeted gene therapy changes angiogenic microenvironment

Glioblastoma - Inhibitory factor may control elements of angiogenesis in brain tumors

Glioma - Ligand gene transfer ineffective treatment strategy for cancer

HIV/AIDS Therapy - Highly active antiretroviral therapy lowers Kaposi sarcoma-associated herpesvirus levels

Head and Neck Cancer - Prognosis of oral carcinoma may depend on microvessel density

Hepatocellular Carcinoma - Underlying liver diseases detected in many cases of liver cancer

Hypercalcemia - NDA reactivated for Ganite; CMC regulatory filings initiated

Immunology - Stressed apoptotic tumor cells stimulate dendritic cells and induce cytotoxic T cells

Infectious Disease - Study reveals prostate as a habitat for multiple viral infections

Legal Issues - Biotech firm in dispute with Canada over genetic test

Lung Cancer - Screening procedure unlikely to be cost-effective

Molecular Biology - UNC studies target molecular defects implicated in cancer, genetic diseases

Multiple Myeloma - Unrelated stem cell grafts effective after antithymocyte globulin treatment

Nutrition - Adolescent diet influences sex hormone levels

Ovarian Cancer - Ex-vivo chemosensitivity analysis leads to dramatic improvement in outcomes

Prostate Cancer - Clusterin modulates cancer cell response to lethal heat exposure

Prostate Cancer - Red clover mimics Asian diet for prostate health

Prostate Cancer - Study elucidates how chromium(VI) may ignite cancer

Public Health - Public supports tobacco control strategies outlined by American Lung Association

Radiation Therapy - Whole-body 18F-FDG PET significantly impacts patient management

Smoking Cessation - Nicotine replacement therapy doesn't increase lung cancer risk, company says

Squamous Cell Carcinoma - Novel virus improves transfection efficacy of head and neck cancer

Stem Cell Transplantation - GvHD and outcome in HLA-identical sibling transplantations for chronic myeloid leukemia

Thyroid Cancer - Phase I/II clinical trial begins for Combretastatin A4 Prodrug

Tumor Therapy - Nitric oxide synthase inhibitors enhance vascular targeting

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