Bladder Tumors
Tumor supressor gene DBCCR1 linked to upregulation of ASML3a
Published in Cancer Weekly, February 4th, 2003
According to a study from the United States, "the function of the tumor suppressor gene DBCCR1 (deleted in bladder cancer chromosome region 1) is unknown despite data supporting an important role for DBCCR1 in bladder tumorigenesis. DBCCR1 has not yet been placed in a protein family or functional pathway. Protein-protein interactions are crucial for almost every aspect of cellular function. We hypothesized that the discovery of DBCCR1 protein binding partners would yield important clues for solving the mystery of DBCCR1 function.
"We used the yeast two-hybrid system to screen an adult human bladder cDNA library for DBCCR1-interacting proteins," stated K.O. Wright and...
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Source: Cancer Weekly (2003-02-04)
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