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Colon Cancer

Iron overload gene tied to increased risk

Published in Cancer Weekly, February 4th, 2003

Researchers at the University of North Carolina at Chapel Hill School of Medicine have found that people with gene mutations associated with abnormally high iron levels are 40% more likely than others to develop colon cancer.

A report of the research found the cancer risk greater in mutation carriers who are older or who consume high quantities of iron.

"Our findings are consistent with the view that taking in too much iron may be an environmental risk factor for colon cancer in some people," said study lead author Dr. Nicholas J. Shaheen, assistant professor of medicine and assistant professor of epidemiology in the UNC School of Public...

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