Published in Cancer Weekly, February 4th, 2003
S. Gaedicke and coauthors showed that "ritonavir, like classical proteasome inhibitors, has antitumoral activities."
"In vitro, ritonavir strongly reduced the rate of proliferation of several tumor cell lines and induced their apoptosis. Nontransformed cell lines and terminally differentiated bone-marrow macrophages were comparatively resistant to the apoptosis-inducing effect," according to study data. "In vivo, ritonavir,...
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