Biomarkers

Researchers report on tumor markers for detecting hepatocellular carcinoma

Published in Cancer Weekly, February 18th, 2003

Researchers in Japan have identified useful biomarkers for detecting hepatocellular carcinoma.

According to their study, "levels of alpha-fetoprotein (AFP), its glycoforms AFP-L3 and AFP-P4, and proteins induced by vitamin K absence or antagonist-II (PIVKA-II) were determined in sera obtained from patients in Yangon General Hospital (20 with hepatocellular carcinoma (HCC), 29 with chronic liver diseases, including 3 with chronic hepatitis and 26 with cirrhosis of the liver, and 9 with other hepatobiliary diseases)."

"Forty-five percent of the patients with HCC had serum AFP levels above 10,000 ng/ml, indicating that nearly half of the HCC patients...

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Source: Cancer Weekly (2003-02-18)

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