Chronic Myelogenous Leukemia
Feto-maternal microchimerism enables safe, effective mismatched stem cell transplants
Published in Cancer Weekly, February 18th, 2003
N. Ochiai and colleagues at Kyoto Prefectural University of Medicine described the case of a 17-year-old boy with CML in blast crisis, who "received a non-T cell-depleted (TCD) HLA haplo-identical three-loci mismatched hematopoietic stem cell transplant (HSCT) from his mother."
"Long-term feto-maternal microchimerism was detected by nested polymerase chain reaction with sequence-specific primer typing" prior to transplantation, Ochiai and coauthors noted.
"Sustained...
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Source: Cancer Weekly (2003-02-18)
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