Chronic Lymphocytic Leukemia
Flow cytometry can evaluate residual disease by measuring BCD5(+) cells
Published in Cancer Weekly, February 18th, 2003
The authors "determined a novel criteria defined by BCD5(+)CD79b(-/low)/total BCD5(+) cells ratio (BCD5(+)R), and compared it with the previous definition of phenotypic remission, based on CD19(+)CD5(+) coexpression with complementarity-determining region 3 polymerase chain reaction (CDR3 PCR) and clonotypic PCR (cPCR). A series of 54 peripheral blood samples from 21 chronic lymphocytic leukemia (CLL) patients in complete hematological remission and 16 samples from normal volunteers were analyzed."
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Source: Cancer Weekly (2003-02-18)
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