Epigenetics

Changes in cancer can be reversed more easily by therapeutic interventions

Published in Cancer Weekly, February 18th, 2003

"Knowledge of the molecular events that occur during the early stages of cancer has advanced rapidly. The initiation and development of cancer involves several molecular changes, which include epigenetic alterations," researchers in the United States report.

"Epigenetics is the study of modifications in gene expression that do not involve changes in DNA nucleotide sequences. Modifications in gene expression through methylation of DNA and remodeling of chromatin via histone proteins are believed to be the most important of the epigenetic changes. The study of epigenetics offers great potential for the identification of biomarkers that can be used to detect and diagnose...

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Source: Cancer Weekly (2003-02-18)

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