Gastric Lymphoma

High frequency of t(11;18) found in MALT disease in Chinese patients

Published in Cancer Weekly, February 25th, 2003

"t(11;18)(q21;q21), the most frequent chromosomal aberration of mucosa-associated lymphoid tissue (MALT) lymphoma, occurs in 30% of gastric patients," researchers in England report.

"Although the translocation is often associated with an aggressive course, it has not been described in transformed MALT lymphomas," wrote S.S. Chuang and colleagues, University College of London, Department of Histopathology.

"We screened 15 gastric MALT lymphomas [three with concurrent or subsequent high-grade transformation and 11 diffuse large B-cell lymphomas (DLBCLs)] in Chinese patients for t(11;18). t(11;18) was found in 9/15 (60%) MALT lymphomas, but not in any...

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Source: Cancer Weekly (2003-02-25)

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