Breast Cancer

Protein is overexpressed in endothelial cells of mouse breast tumor vessels

Published in Cancer Weekly, March 4th, 2003

According to recent research from Switzerland, "angiogenesis is a key process in a variety of human diseases, including cancer. The ability to target selectively the tumor vasculature is potentially useful for the diagnosis and treatment of cancer. Still, little information is available regarding markers that are restricted to the endothelial cells of tumor vessels."

"cDNA array technology allows simultaneous analysis of relative expression levels of a broad spectrum of genes in two related cell populations. We used this technology with the aim of identifying markers specific for tumor ECs (TECs)," wrote M.C. Schmid and colleagues, University of Bern.

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Source: Cancer Weekly (2003-03-04)

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