Stem Cell Transplantation
Donor T-cell TNF involved in graft-versus-host and antitumor activity
Published in Cancer Weekly, March 18th, 2003
"Previous studies in murine bone marrow transplantation (BMT) models using neutralizing anti-tumor necrosis factor (TNF) antibodies or TNF receptor (TNFR)-deficient recipients have demonstrated that TNF can be involved in both graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL)," explained Cornelius Schmaltz and colleagues at the Memorial Sloan-Kettering Cancer Center and Cornell University in New York City, the Thomas Jefferson Medical Center in Philadelphia, and the University of...
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Source: Cancer Weekly (2003-03-18)
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