Malignant Melanoma

Pigmented atypical fibroxanthoma may be easily mistaken for the malignancy

Published in Cancer Weekly, March 25th, 2003

Pigmented atypical fibroxanthoma may be easily mistaken for the malignancy.

"Nine cases of an unusual presentation of atypical fibroxanthoma that we previously termed pigmented atypical fibroxanthoma are reported. Pigmented atypical fibroxanthoma can be easily mistaken for malignant melanoma both clinically and histopathologically," researchers in Germany report.

The researchers concluded: "The resemblance of pigmented atypical fibroxanthoma to melanoma is secondary to the ability of neoplastic cells to ingest and degrade erythrocytes following intratumoral hemorrhage and to accumulate hemosiderin in their cytoplasm. The histopathologic diagnosis...

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Source: Cancer Weekly (2003-03-25)

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