Oncogenes

Possible early gene involved in the development of cancer

Published in Cancer Weekly, March 25th, 2003

Mayo Clinic is one of three research laboratories around the world to independently discover that a gene named MDC1 appears to play a pivotal role in the development of cancers - including breast cancer.

The Mayo Clinic finding is significant because the MDC1 gene appears to be closer than most others investigated so far to the earliest events that go wrong in a healthy body and cause cells to turn cancerous. Specifically, MDC1 is a "checkpoint protein" that appears to guard against abnormal cells reproducing themselves, a process that leads to cancers.

The Mayo Clinic results - along with those from the other laboratories in Cambridge, England, and...

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Source: Cancer Weekly (2003-03-25)

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