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Breast Cancer

An immune-competent murine model offers a new way to study cancer

Published in Cancer Weekly, March 25th, 2003

An immune-competent murine model offers a new way to study cancer.

According to recent research from Canada, "estrogen is important for breast carcinogenesis and the majority of breast cancers maintain hormone dependency. Estrogen has the ability to stimulate both breast epithelial cell growth and angiogenesis, and a well-characterized in vivo cancer model where these functional interactions can be studied is lacking."

"We demonstrate estrogen dependent angiogenesis, growth in vivo, and proliferation in vitro, in explants from polyoma middle T transgenic mouse mammary tumors," wrote C. Dabrosin and colleagues, McMaster University, Department of...

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