Cancer Genetics

The risk for breast cancer in Chinese women is linked to a gene polymorphism

Published in Cancer Weekly, March 25th, 2003

The risk for breast cancer in Chinese women is linked to a gene polymorphism.

According to recent research from Singapore, "angiotensin II has been shown to have possible mitogenic and angiogenic effects in human cell lines and animal models of breast cancer. It is converted from its precursor to its active form by the angiotensin I-converting enzyme (ACE). A recent epidemiological study observed lower breast cancer incidence in female users of ACE inhibitors relative to nonusers with comparable cardiovascular conditions."

"To study the hypothesis that reduced ACE activity is associated with reduced risk of breast cancer, we conducted a nested,...

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Source: Cancer Weekly (2003-03-25)

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