Cancer Weekly

Breast Cancer Diagnosis - NIST, UW-Madison research may lead to new breast cancer detection methods

Cancer Metastasis - Thrombin generation correlates with biomarkers in advanced prostate cancer

Bone Cancer - Pulmonary metastasis can arise after surgery for osteosarcoma

Cancer Markers - Disruption of the HIC1 gene may predispose mice to gender-specific malignancy

Colon Cancer Screening - Potential blood test could predict risk

Rhabdomyosarcoma - Gene that drives apoptosis also plays key role in development of skeletal muscle

Acute Lymphoblastic Leukemia - Bone marrow grafts may be best option with matched unrelated donors

Adnexal Carcinoma - An unusual case of microcystic adnexal carcinoma described

Anticancer Therapeutics - Anthrapyridazone derivatives are active, even on multidrug resistant cells

Autoimmune Disorders - CTLA-4 exon 1 polymorphism G was found in leukemic hemolytic anemia patients

B Cell Leukemia - CMV disease can mimic an acute B-precursor lymphoblastic leukemia

Bence Jones Myeloma - A serum test is more consistently reliable than the standard urine test

Bone Marrow - The alcaloid swainsonine has a significant stimulatory effect on bone marrow

Bottled Water - Migration of mutagens/carcinogens from PET bottles to water found

Brain Cancer - Injection of DTI-015, a mix of BCNU in ethanol, stabilized active gliomas

Brain Tumors - Differentiating demyelinating lesion from neoplasm requires caution

Breast Cancer - Data provide evidence of how to conduct web-based interventions

Breast Cancer - Doppler imaging may have value for differentiating focal breast lesions

Breast Cancer - Incidence of "lobular" disease increasing

Breast Cancer - Local recurrence before 2 years following surgery predicts the worst outcome

Breast Cancer - Metastasis and tumor growth suppression achieved with propolis in mouse model

Breast Cancer - New technologies improve ability to diagnose and excise breast cancer

Breast Cancer - Researchers call for better studies on environmental links

Breast Cancer - State variation in mortality rates due to later stage at presentation

Breast Cancer - Tamoxifen and a farnesyl transferase inhibitor can have synergistic effects

Breast Cancer - The biology of breast cancer genes will impact disease management

Breast Cancer - Thymidylate synthase and thymidine are valid markers for selecting therapy

Breast Cancer Survival - Axillary lymph node drainage appears to be an important prognostic factor

Bronchial Adenocarcinoma - Case report: Metastatic metamorphopsia of the right eye

Bronchogenic Carcinoma - Lung transplantation for bronchogenic carcinoma is not supported

CNS Lymphoma - Expression of BCA-1 may influence tumor development and localization to CNS

Cancer Antagonists - The estrogen product 2-methoxyestradiol is a promising anticancer agent

Cancer Gene Therapy - Peptide fusion improves the efficacy of thymidine kinase suicide gene therapy

Cancer Metastasis - Docetaxel enhances the effect of the angiogenesis inhibitor TNP-470

Cancer Metastasis - Neck lymph node metastasis risk relates to ill defined extracapsular spread

Cancer Mortality - Behavior changes could sharply cut cancer death rates

Cancer Predictors - Thromboembolism precedes cancer; should be considered risk marker

Cancer Research - CD40-directed gene therapy shows prospects for treating human cancers

Cancer Research - Fruit fly metalloproteinase controls tissue remodeling, not embryo development

Cancer Screening - Men more likely to be screened for prostate than for colorectal cancer

Cancer Therapy - Cyclooxygenase inhibitors decrease the angiogenic potential of tumor cells

Cancer Therapy - Plasminogen activators and captopril combine to diminish angiogenesis in tumors

Cancer Therapy - South Africa approves natural interferon

Cancer Vaccine - Cancer treated using vaccines in mixed allogeneic bone marrow chimeras

Cardiology - Researchers report a thymic carcinoid mimicking acute aortic dissection

Cell Cycle - Nuclear phosphatase and tensin homologue is associated with G0-G1

Cervical Cancer - A rare case of metastasis to the scalp from carcinoma of the cervix is presented

Cervical Cancer - Common cell lines were analyzed cytogenetically for all aberrations

Cervical Cancer Vaccine - Dendritic cell vaccine shows promise against cervical cancer

Cervical Carcinoma - Growth of HeLa cells enhanced by H₂ O₂ at relatively low concentrations

Chemotherapy - Antinausea drug will likely get approval in U.S.

Chemotherapy - Older, younger febrile neutropenic patients have similar infection rates

Chronic Myeloid Leukemia - Medical journal editorial dubs Gleevec "gold standard"

Colon Cancer - Major study shows aspirin can reduce polyp return in GI cancer patients

Colon Cancer - Reduced syndecan-2 expression correlates with lower colon cancer tumorigenicity

Colon Cancer - Study explores genetic counseling in families with hereditary disease

Colon Cancer - Tea complements drugs in treatment

Colon Cancer - Western diet a chief culprit

Colon Cancer Screening - Patients prefer "virtual" colonoscopy but dislike preparation

Colorectal Cancer - CDC study finds colorectal cancer screening rates remain low

Colorectal Cancer - Markers of susceptibility to some meat and caffeine carcinogens are found

Colorectal Cancer - Screening tests effective and can save lives

Complementary and Alternative Medicine - Preparations can lead to kidney failure and the need for dialysis or transplant

Dermatology - A protein cluster links UVB and the induction of growth factor in skin cells

Environmental Toxins - New program to study possible environmental causes of cancer

Ewing Sarcoma - Detecting random aneuploidy may predict tumor relapse

Ewing Sarcoma - Femur cancer treated with surgery, with or without radiation, worked best

Eyelid Histiocytoma - Rare case of malignant fibrous histiocytoma of the eyelid reported

Familial Retinoblastoma - RB1 mutation-screening method enhances care for the affected and saves money

Food Ingestion - Foods and their heating or processing may increase cancer risk

Fungal Structures - Researchers study the fungus Pulveroboletus ravenelii in mouse mammary culture

Gastric Adenocarcinoma - The risk of cancer associated with virulent H. pylori may be underestimated

Gastroenterology - Gastrointestinal disorders can affect the genitourinary system

Gastroenterology - Vascular endothelial growth factor can be identified in digestive tumors

Gene Targets - RNA interference may be more potent than antisense RNA in human cancer cells

Glioma - Antisense to cathepsin L impairs human brain tumor cell invasion

Gliomal Cell Surface - Stripping proteoglycans of sulfation leads to adhesional and migrational changes

Gunther Disease - Congenital erythropoietic porphyria can occur with cystic hygroma

Hepatic Metastasis - Interleukin-18 binding protein therapy can neutralize cancer adhesiveness

Hepatocellular Carcinoma - Global distribution is uneven, and annual disease mortality is same as incidence

Hepatocellular Carcinoma - Human CRYL1 is an enzyme-crystallin found downregulated in some liver cancers

Human Papillomavirus - Researchers test vaccine in hopes of cutting cervical cancer rate

Hypospadias - Possible association of verrucous scrotal carcinoma, hypospadias reported