Published in Cancer Weekly, April 1st, 2003
"Clinical outcome of cancer patients is mainly determined by the rate of metastasis and, also by primary tumor growth. Formation of extracellular matrix and interactions of neoplastic and non-neoplastic (host) cells in solid tumors have been shown to be essential for these processes. One result of such interactions is the outgrowth of new blood vessels from existing ones, angiogenesis, to provide the tumor tissue with oxygen and nutrients," researchers in Netherlands report.
"It is assumed that the neovascular bed also facilitates the escape of metastatic cells from the primary...
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