Published in Cancer Weekly, April 1st, 2003
"Single nucleotide polymorphisms are the most abundant genetic markers in the human genome whose analyses can be easily conducted on a large scale. Most established methods for high-throughput single nucleotide polymorphism analyses are qualitative and are not suitable for genetic analysis of archived tumor specimens, which have compromised tissue integrity and normal tissue contaminations," researchers in the United States report.
"Recent studies have focused on the development of quantitative methods for single nucleotide polymorphism analyses that can tolerate such...
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