Published in Cancer Weekly, April 1st, 2003
"It is considered that resection of the primary tumor induces activation of systemic angiogenesis and enhances progression of remote metastasis. The authors show that resection of the primary osteosarcoma tumor enhances progression of pulmonary metastasis in animal osteosarcoma models," wrote T. Tsunemi and colleagues, Sapporo Medical University, School of Medicine.
"Matrigel plug neovascularization assay...
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