Urology
Adenoviral-mediated retinoblastoma 94 localizes to bladder cancer cells
Published in Cancer Weekly, April 8th, 2003
According to a study from the United States, "retinoblastoma (RB)94, which lacks the NH2-terminal 112 amino acid residues of the full-length RB protein (RB110), is a more potent tumor and growth suppressor than RB110."
"In this study, Ad-RB94, but not Ad-RB110, produced marked growth inhibition, cytotoxicity, caspase-dependent apoptosis, and G(2)-M block in the human RB-negative, telomerase-positive bladder cancer cell line UM-UC14. This effect was completely inhibited by pretreatment with caspase inhibitors (p<0.0001)," stated X.Q. Zhang and coauthors, University of Texas,...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2003-04-08)
More Articles from Cancer Weekly
- Cancer Therapy
Researchers discover new method to treat cancer - Liver Cancer
Metastasis gene may be useful for diagnosis and treatment - Biomarkers
Several genes may be reliable markers for primary liver cancer - Breast Cancer
The tumor suppressor maspin inhibits angiogenesis in breast malignancies - Cancer Screening
Hispanic women in border states less likely to receive screening for breast, cervical cancers - Lung Cancer
Treatment improves with better timing - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
