Burkitt Lymphoma
Gamma irradiation induces Epstein-Barr virus reactivation
Published in Cancer Weekly, April 8th, 2003
"Epstein-Barr virus (EBV), a member of the gamma-herpesvirus family, is involved in the development of several diseases, and the infection is believed to persist for life in latent form. Ionizing radiation at clinically relevant doses may increase the amount of virus reactivation in B cells, and the combination of radiation with stress could amplify EBV reactivation. In vitro experiments were performed on several cell lines, including EBV(+) Burkitt lymphoma cells," researchers in France report.
"The presence of the immediate-early protein ZEBRA, which is a hallmark of EBV reactivation, was...
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Source: Cancer Weekly (2003-04-08)
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