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Cancer Therapy
Thymosin beta-15 shows strong antiangiogenic potential in laboratory assays
April 22nd, 2003
Thymosin beta-15 shows strong antiangiogenic potential in laboratory assays. According to recent research published in the journal Peptides, "Thymosin beta-15 (Tbeta15), a 44 amino acid peptide (MW=5173) localized in human prostate and breast cancer tissues, was successfully synthesized in multigram quantities using Fmoc solid-phase peptide synthesis." "The synthesized product was shown to have the tight structure by ESI and MALDI mass spectral techniques and amino acid analysis. Relatively high yield was achieved, which might be due to enhanced acid stability of the p-cyanotrityl resin used," according to V. Koutrafouri and colleagues,...
Source: Cancer Weekly (2003-04-22)
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