Cancer Weekly
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Colon Cancer
Carcinoembryonic antigen and cytokeratin 20 can warn of peritoneal recurrence
April 22nd, 2003
Postsurgical peritoneal micrometastasis can be detected and recurrence may therefore be predicted using RT-PCR for carcinoembryonic antigen and cytokeratin 20 to follow up colon cancer patients. According to recent research from Japan, "Peritoneal recurrence after curative resection of malignant tumor with negative cytology is considered to be caused by microscopic dissemination of the exfoliated cancer cells from primary tumors to serosal surfaces at the time of operation, not detectable with conventional diagnostic tools. "We applied the reverse transcriptase-polymerase chain reaction (RT-PCR) for carcinoembryonic antigen (CEA) and cytokeratin 20...
Source: Cancer Weekly (2003-04-22)
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