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Cancer Weekly

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Esophageal Stricture



Chemoradiotherapy can improve squamous cell carcinoma patient survival



April 22nd, 2003

Esophageal stricture due to malignant T3 and T4 squamous cell carcinoma can be resolved enough to increase patient survival somewhat by chemoradiotherapy.

According to a study from Japan, "We retrospectively investigated the efficacy and feasibility of concurrent chemoradiotherapy for patients with severe dysphagia caused by esophageal squamous cell carcinoma.

"Concurrent chemoradiotherapy was performed in 57 patients with T3 or T4 disease containing M1 lymph node (LYM) disease. Chemotherapy consisted of protracted infusion of 5-fluorouracil (5-FU) 400 mg/m2/24 h on days 1-5 and 8-12, combined with 2 h infusion of cisplatin (CDDP) 40...


Source: Cancer Weekly (2003-04-22)

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