Rhabdomyosarcoma
Synthesized Pt(II) complexes should be studied further for antitumor activity
Published in Cancer Weekly, May 20th, 2003
"In this study, six Pt(II) complexes bearing 5(6)-H or -CH3-2-phenyl or -(2'-pyridyl) or -mercaptomethylbenzimidazole ligands as,carrier groups' were synthesized and characterized by elemental analysis, IR and H-1-NMR spectra and evaluated for their preliminary in vitro cytotoxic activity to the human RD Rhabdomyosarcoma cell line and mutagenic properties in Salmonella typhi murium strains TA 98 and TA 100 in the absence of the S9 rat liver fraction," scientists in Turkey report.
"The preliminary test results showed that the complexes had slightly greater cytotoxic...
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Source: Cancer Weekly (2003-05-20)
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