Breast Cancer

Mutations in the C/EBPD gene are relatively uncommon in human breast cancer

Published in Cancer Weekly, May 20th, 2003

Mutations in the C/EBPD gene are relatively uncommon in human breast cancer.

"Single strand conformation polymorphism (SSCP) analysis was performed on genomic DNA from 97 human breast cancer samples and 10 breast cell lines to screen for mutations in the single exon C/EBPD gene," researchers in the United States report.

"Three C-->T transitions resulting in silent mutations were detected in three individual breast cancer samples. One breast cancer sample also contained a G-->T transversion (Q253H)," wrote D.H. Tang and colleagues, The Ohio State University, Department of Veterinary Bioscience.

"The SUM-52PE cell line...

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Source: Cancer Weekly (2003-05-20)

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