Published in Cancer Weekly, May 27th, 2003
"Sentinel node (SN) status is the most important prognostic factor for localized melanoma. Usually, patients with Breslow thickness of less than 1.0 mm are not included in SN protocols," investigators in Brazil report.
"However, the literature presents a rate ranging from 3 to 7% of nodal recurrence in thin melanoma. Ulceration, regression and high mitotic rate have been considered to be indications for an SN biopsy. The metastatic potential of the vertical growth phase is uncertain," stated R.S. Oliveira and colleagues, Federal University of Sao Paulo.
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