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Cancer Therapy

Several chemopreventive drugs strike down common angiogenic mechanisms

Published in Cancer Weekly, May 27th, 2003

Several chemopreventive drugs strike down common angiogenic mechanisms.

According to recent research published in the International Journal of Biological Markers, "tumors growing within the host form dynamic aberrant tissue that consists of host components, including the stroma, an expanding vasculature and often chronic inflammation, in addition to the tumor cells themselves."

"These host components can contribute to, rather than limit, tumor expansion, whereas deprivation of vessel formation has the potential to confine tumors in small, clinically silent focim" said U. Pfeffer and colleagues, National Cancer Research Institute, Molecular...

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