Epithelial Cell Carcinoma
Epithelial cell carcinoma occurs in two CML patients under imatinib treatment
Published in Cancer Weekly, May 27th, 2003
"Imatinib (Glivec, formerly known as STI571) effectively blocks the ATP-binding site of the bcr/abl fusion protein thereby inactivating selectively the tyrosine kinase activity of bcr/abl," researchers in Germany report.
"Therefore, it is a promising drug in Philadelphia chromosome-positive chronic myeloid leukemia showing high hematologic and cytogenetic response rates combined with a mild toxicity profile," wrote G. Baskaynak and colleagues, Humboldt University.
The researchers concluded: "Here we report two cases of squamous cell carcinoma of the...
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Source: Cancer Weekly (2003-05-27)
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