Non-Hodgkin Lymphoma

Myeloablative purged stem cell autografts effective against low-grade disease

Published in Cancer Weekly, June 10th, 2003

Myeloablative purged stem cell autotransplantation is effective against low-grade non-Hodgkin lymphoma.

Researchers in France conducted a study to "evaluate the results of high-dose therapy followed by purged autologous stem cell transplantation (ASCT) for patients with low-grade follicular non Hodgkin's lymphoma (LGFL), and the prognostic significance of PCR detection of residual Bcl-2/IgH-positive cells after ASCT."

"Between 1992 and 1998, 49 patients with LGFL received total body irradiation and high-dose cyclophosphamide followed by purged ASCT," according to B. Mahe and colleagues at the University of Nantes. "PCR amplification of the Bcl-2/IgH...

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Source: Cancer Weekly (2003-06-10)

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