Breast Cancer
The CYP3A4*1B variant is related to the onset of puberty
Published in Cancer Weekly, June 10th, 2003
According to published research from the United States, "Breast development, one of the first signs of puberty, is closely associated with age at menarche; and early menarche is in turn a well-established risk factor for female breast cancer.
"We examined the relationships between the onset of puberty and gene variants for certain enzymes that regulate hormone metabolism among 137 healthy 9-year-old girls from two pediatric clinics," wrote F.F. Kadlubar and colleagues, National Center for Toxicology Research, Division of Molecular Epidemiology.
"High-activity CYP17 alleles,...
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Source: Cancer Weekly (2003-06-10)
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