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Non-Hodgkin Lymphoma

Zevalin, a radioimmunotherapeutic, shows high response, durable remissions

Published in Cancer Weekly, June 24th, 2003

The final report from a clinical trial of the radioimmunotherapy Yttrium-90 ibritumomab tiuxetan (Zevalin) presented at the 39th annual meeting of the American Society of Clinical Oncology (ASCO) concluded that Zevalin produces high response rates and durable remissions when used as a treatment for low-grade, follicular, and transformed non-Hodgkin's Lymphoma (NHL).

Responses extending beyond the 4-year-mark are described with the average duration in 34% of the patients that had a complete response to Zevalin (vs. 16% in the control group) currently approaching 2 years. The updated trial results are based on a pivotal clinical trial that included 143 patients randomized...

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