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Cancer Vaccine

Researchers find evidence of clinical activity in Tricom in advanced cancers

Published in Cancer Weekly, June 24th, 2003

Georgetown University researchers presented clinical data confirming the safety and the first evidence of clinical activity of Therion Biologics' Tricom therapeutic vaccines.

Proprietary to Therion, Tricom consists of three costimulatory molecules designed to optimize the immune response necessary for tumor destruction when delivered as part of the company's pox virus-based vaccines. This approach, delivered in a "prime-boost" dosing regimen, induced tumor-specific immune responses and significant clinical benefit in some patients with CEA-expressing cancers (in this study, predominantly gastrointestinal cancers).

Specifically, disease stabilization...

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