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Cell Biology

Hydrogen peroxide formation is essential to ethanol-induced angiogenesis

Published in Cancer Weekly, July 8th, 2003

Hydrogen peroxide formation is essential to ethanol-induced angiogenesis.

"This report focuses on the identification of the molecular mechanisms of ethanol-induced in vitro angiogenesis. The manipulation of angiogenesis is an important therapeutic approach for the treatment of cancer, cardiovascular diseases, and chronic inflammation. Our results showed that ethanol stimulation altered the integrity of actin filaments and increased the formation of lamellipodia and filopodia in SVEC4-10 cells," according to U.S. government researchers.

"Further experiments demonstrated that ethanol stimulation increased cell migration and invasion and induced in...

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