Cancer Metastasis

Rogue genes speed breast cancer spread to bone marrow

Published in Cancer Weekly, July 15th, 2003

Researchers have peered inside breast cancer's toolbox and identified a set of rogue genes that accelerates the spread of cancer from its primary site in the breast to a secondary location in bone marrow.

The genes identified by the scientists are distinct from those that spawn the initial tumor, which invites speculation about whether different cancers bear unique "gene expression signatures" that increase the probability that a cancer will spread in a process called metastasis.

Metastasis occurs when cells from a primary tumor break off and invade another organ. It is the deadliest transformation that a cancer can undergo, and therefore researchers...

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Source: Cancer Weekly (2003-07-15)

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