Cancer Metastasis
The thrombin receptor PAR-1 is suspected of influencing melanoma dissemination
Published in Cancer Weekly, July 22nd, 2003
According to a study from the United States, "To determine treatment strategies and predict the clinical outcome of patients with melanoma it is important to understand the etiology of this disease. Recently, there has been some insight into molecular basis of melanoma including identification of a few of the regulatory factors and genes involved in this disease. For instance, the transcription factor AP-2 plays a tumor suppressor-like role in melanoma progression by regulating genes involved in tumor growth and metastasis."
"Previously, we have shown that the progression...
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Source: Cancer Weekly (2003-07-22)
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