Chronic Myeloid Leukemia
Novel T-cell clone targets malignant stem cells
Published in Cancer Weekly, July 22nd, 2003
"The therapeutic effect of a human leucocyte antigen (HLA)-identical allogeneic stem cell transplantation (allo-SCT) for the treatment of hematological malignancies is mediated partly by the allogeneic T cells that are administered together with the stem cell graft," scientists in the Netherlands explained. "Chronic myeloid leukemia (CML) is particularly sensitive to this graft-versus-leukemia (GVL) effect."
"Several studies have shown that in allogeneic responses both CD4 and CD8 cells are capable of strong antigen-specific growth inhibition of leukemic progenitor cells, but that CD4 cells mainly...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2003-07-22)
More Articles from Cancer Weekly
- Breast and Lung Cancer
Breast, lung cancers are associated with decreased blood cell amino acid content - Leukemia
NUP98-HOXD13 can be implicated in leukemic transformation - Breast Cancer
Higher excretion levels of estrogens and androgens increase breast cancer risk - Melanoma
Acquired nevus could be precursor to melanoma - Sarcoma
Postoperative follow-up is related to tumor grade and size - Squamous Cancer
Hypercalcemia of malignancy is an ominous prognostic sign - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
