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Leukemia

Myelodysplastic syndrome can occur after treatment for promyelocytic leukemia

Published in Cancer Weekly, August 5th, 2003

Myelodysplastic syndrome can occur after treatment for promyelocytic leukemia.

According to recent research published in the journal Cancer Genetics and Cytogenetics, "Acute promyelocytic leukemia (APL) represents a biologic and clinically well-defined subtype of acute nonlymphocytic leukemia with specific morphologic and karyotypic characteristics.

"Although secondary leukemia and myelodysplastic syndromes (MDS) are the most frequent secondary neoplasms following chemotherapy for acute leukemia, their development after complete remission in patients with APL is uncommon. We describe the clinical and genetic features of two APL patients who...

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