Lung Cancer
Two genes may interact to increase risk in smokers
Published in Cancer Weekly, August 5th, 2003
Researchers have long sought to explain why some smokers get lung cancer and others do not. In one of the first studies to suggest that the interaction of two genes may play a role, researchers at the University of Pittsburgh Cancer Institute (UPCI) have found that inheriting alterations in both a DNA repair gene and a cyclin D1 gene may increase the risk of lung cancer in those exposed to tobacco carcinogens.
The preliminary findings were presented at a poster session at the annual meeting of the American Association for Cancer Research.
"In our study, we found a strong correlation between genetic polymorphisms in two genes and lung cancer risk,"...
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Source: Cancer Weekly (2003-08-05)
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