Mutation CDP may allow tumor growth

According to published research from Australia, "Leiomyomas are the most common gynecologic tumors in women, but very little is known about their molecular pathology.

"We used single-stranded conformational polymorphism/heteroduplex analysis to analyze 42 unselected uterine leiomyomas for somatic mutations in all coding exons of the gene encoding CCAAT displacement protein (CDP), as well as exons 5-8 of TP53 and codons 1-36 and 38-80 of KRAS," wrote M.I. Patrikis and colleagues, Peter MacCallum Cancer Institute.

"No somatic mutations were identified in either TP53 or KRAS, indicating that...

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