Published in Cancer Weekly, August 5th, 2003
The Phase I study uses an antibody directed at the MUC1 protein, which is exposed on the surface of cancer cells in more than 90% of women who have breast cancer. In normal tissues, MUC1 is a protein that is literally sugar-coated, being completely surrounded by carbohydrate molecules. In rapidly growing cancer cells, the sugar structures do not form correctly and the protein core of MUC1 is exposed. Researchers believe this...
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