Stem Cell Research
Endothelial progenitor cell tumor homing relies on multiple steps for fruition
Published in Cancer Weekly, August 12th, 2003
"Tissue neovascularization involves recruitment of circulating endothelial progenitor cells that originate in the bone marrow. Here, we show that a class of embryonic endothelial progenitor cells (Tie-2(+), c-Kit(+), Sca-1(+), and Flk-1(-)/low), which were isolated at E7.5 of mouse development at the onset of vasculogenesis, retain their ability to contribute to tumor angiogenesis in the adult," scientists in Germany reported.
"Using intravital fluorescence videomicroscopy, we further defined the multistep process of embryonic endothelial progenitor cell (eEPC) homing and...
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Source: Cancer Weekly (2003-08-12)
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