Oncogenes

Scientists demonstrate new method for discovering cancer gene function

Published in Cancer Weekly, August 26th, 2003

Using a new approach for dissecting the complicated interactions among many genes, scientists at Dana-Farber Cancer Institute have discovered how a common cancer gene works in tandem with another gene to spur the unchecked growth of cells.

The researchers said the technique was so useful in solving a longstanding puzzle that it may expedite the discovery of other such gene interactions that lead to cancer, and could accelerate the development of new cancer drugs.

The report in the August 8, 2003, issue of Cell describes how the method was used in identifying what additional genes are affected by the common oncogene, cyclin D1, when it makes...

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Source: Cancer Weekly (2003-08-26)

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