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Lung Cancer

Protein profile predicts prognosis

Published in Cancer Weekly, August 26th, 2003

In the future, many cancer scientists and physicians believe that a "molecular fingerprint" of an individual's cancer may be used to diagnose that patient's disease and tailor therapy.

Researchers at Vanderbilt have moved a step closer to that scenario with the identification of a distinct pattern of expression of 15 proteins in lung cancers that can predict a poor prognosis or a good prognosis. All patients in the poor prognosis group had died 1 year after diagnosis, while all patients in the good prognosis group were still alive. Median survival, the point at which half the patients were still alive, was 6 months for the poor prognosis group, compared to 33 months for...

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